Session 1A: Carbon nanotube toxicity

Session chairs

Jun Kanno, M.D., Ph.D., Director, Japan Bioassay Research Center (JBRC), Japan Organization of Occupational Health and Safety and Visiting Researcher, National Institute of Health Sciences (NIHS), jun-kanno@jbrc.johas.go.jp

Nicklas Raun Jacobsen, M.Sc., Ph.D. Senior Researcher, the National Research Centre for the Working Environment (NRCWE), Copenhagen, Denmark, nrj@nrcwe.dk

Session abstract

The most interesting group of materials refined in the era of nanotechnology is carbon nanotubes (CNT). With lightness, conductivity and extreme strength and stability these hollow single- or multi-layered tubes are already found in many consumer and industrial products. With the low density and small needle size of CNT they can be aerosolized under workplace conditions thus making inhalation exposure likely during production, processing etc.

New advances are continuously being published in the area of toxicology of CNT. However, although one CNT material has been classified as a possible carcinogen to humans, the potential to cause health effects in humans have not been fully investigated.

In this session we will address and focus on the current state of knowledge on CNT toxicity. We encourage submission of abstracts on latest discoveries of all types of CNT related toxicity. Oral presentations will have a focus towards but are not limited to areas such as inhalation exposure, genotoxicity, mutagenicity and cancer.

Session program

  • Pulmonary toxicity of multi-walled carbon nanotubes in rats, a subacute inhalation study – Invited presentation
    Laurent Gaté
  • Demonstration of carcinogenicity of multi-walled carbon nanotubes by trans-tracheal intrapulmonary spray (TIPS) method in the rat – A simple carcinogenicity screening test of fibrous carbon nanomaterials – Invited presentation
    Hiroyuki Tsuda
  • The recent industrial applications of CNTs considering toxicological evaluations and Redox Potential estimating ROS toxicity – Invited presentation
    Shuji Tsuruoka
  • Long-fibre carbon nanotubes induce pleural mesothelioma via silencing and/or loss of key tumour suppressor genes
    Tatyana Chernova
  • Fragmented centromeres, translocations, aneuploidy, aberrant mitotic spindles, and fragmented centrosomes in human lung epithelial cells exposed to Mitsui-7, heat-treated, and nitrogen-doped multi-walled carbon nanotube
    Linda Marie Sargent